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Zofran Birth Defects

The filing of Zofran lawsuits is the result of medical practitioners prescribing the popular ondansetron-based drug Zofran to pregnant women for the treatment of morning sickness. Several studies have linked Zofran with the increasing risk of birth defects.

The families of women who have used Zofran during pregnancy are currently suing GlaxoSmithKline, the manufacturer of the drug, for illegally marketing a drug for a use that has not approved by the Food and Drug Administration (FDA).

Attorneys for those harmed by Zofran are using the many studies of Zofran establishing adverse side effects as evidence in the Zofran lawsuits.

Updates on Zofran Lawsuits

The FDA warned about the use of Zofran for pregnant women with the problem of morning sickness causing electrolyte imbalance as it can cause heart problems to newborn babies along with various other side effects.

It has been proven through various studies that by taking Zofran during pregnancy, the risk of heart problem among newborn babies can increase more than 60% and doubles the risk of holes in the heart.

Many cases of babies with heart problems due to consumption of Zofran during pregnancy have come to light. All of these incidents resulted in legal problems for GlaxoSmithKline as the patients and their families are filing Zofran lawsuits against the manufacturer.

One of these petitioners is a woman from Massachusetts who gave birth to a baby with facial deformities, three heart defects, and webbed toes along with various other birth defects after taking Zofran in her first trimester of pregnancy.

Birth Defects Caused by Zofran

According to various researchers, the use of Zofran during pregnancy has been directly linked to various heart defects along with other various birth defects. Some of the most shocking birth defects noticed so far resulting into Zofran lawsuits include:

  • Children with holes in their heart, which resulted in their death.
  • Infants were found with the problem of intrauterine growth restriction (IUGR). Several of these infants weighed even less than 4.5 pounds due to their poor growth in the womb during gestational period.
  • Numerous incidents of kidney malfunctioning along with heart defects have also been reported.
  • The problem of musculoskeletal abnormality was also detected in one baby.
  • It has also been established that Zofran can cause jaundice, mouth deformity, heart defects like atrial septal defect or hole in the heart and heart murmur when the drug is taken during pregnancy.

The Basic Reasons for Zofran Lawsuits

Zofran, developed by GlaxoSmithKline, was approved for use in the United States in 1991, and in 2006, its first generic version received approval to treat nausea and vomiting. Ondansetron, the basic ingredient of Zofran, is considered as an approved treatment for vomiting and nausea for patients undergoing chemotherapy and other cancer treatments. Although the FDA never approved Zofran for the treatment of morning sickness in pregnant women, many doctors prescribed Zofran for this off label purpose.

Zofran initially acts on your nervous system by increasing gastric emptiness and blocking serotonin to reduce the problems of vomiting and nausea. Medical practitioners prescribed the drug to pregnant women, as 70-80% women experience the problem of morning sickness, vomiting and nausea during the first trimester of their pregnancy. Only in case of uncontrolled vomiting they are required to be hospitalized due to deficiency of nutrition, severe dehydration, weight and muscle loss and electrolyte imbalance as they can increase the health risk for fetus as well as the mother.

The FDA has not approved Zofran to be used during pregnancy as they have classified it as a Category B drug for pregnancy, which shows that it was not found to be safe during initial studies. Thus, Zofran has been linked to fatal side effects for pregnant women and their newborn babies. If pregnant women want to know about the workings of Zofran, they should consult a qualified and experienced healthcare provider.

Expected Birth Defects of Zofran Resulting in Zofran Lawsuit

It has been proven through various studies that Zofran passes from mother to fetus in significant amounts vary rapidly through the placenta. Zofran remains active for a longer time in the fetus as compared to the mother. For this reason, several newborn babies are found suffering from various birth defects caused by Zofran, which was taken by their mother during the first trimester of their pregnancy.

Brief information about the main birth defects caused by Zofran is given here under for your consideration:

  • Risk of birth defects: Australian researchers established that there is a 20% increase in the risk of birth defects linked to the usage of Zofran during the first trimester of pregnancy.
  • Risk of Heart Defects: According to various studies, Zofran is linked to two types of heart defects—ventricular septal defect, or opening in the wall between upper left and upper right chamber of the heart, and arterial septal defect, or hole in the lower left and lower right chamber of the heart.
  • Risk of Heart Murmur: The use of Zofran during the first trimester of the pregnancy can cause extra abnormal whooshing or a clicking sound in the heart, which can be heard by using a stethoscope. It is considered as a heart defect even if it is found harmless.
  • Risk of Cleft Palate: Various researches have proven that consumption of Zofran during pregnancy increases the risk of cleft palates in babies by 50%.
  • Risk of Cleft Lip: Like cleft palate, cleft lip involves a gap in the upper lip, which in severe cases can cause dental defects and even non-existence of the upper lip.

Other birth defects caused by Zofran may include:

  • musculoskeletal defects
  • kidney defects
  • fetal growth restriction or poor growth in the womb
  • hypospadias
  • hydronephrosis

If you or any of your loved ones have a child with birth defects due to the use of Zofran during the first trimester of pregnancy then they may be eligible to file a Zofran lawsuit. Contact the attorneys at Abbott Law Group today for a free case evaluation.